1- Disha Vakani and Mayur Vakani, who play reel life siblings, are brother and sister in reality
2- Shyam Pathak, who essays the role of Popatlal, a man tagged with the label of bachelor forever, is married in real and have 3 children.
3- Dilip Joshi, who plays the role of Jethalal, is older in age than his on-screen father(bapuji) Amit Bhatt
4- Atmaram Tukaram Bhide(Mandar Chandwadkar) who plays the role of Bhidhe Master is a mechanical engineer in real life. He worked as an engineer in Dubai for 3 years. This skillful person is also a blogger.
5- Sonalika Joshi who plays the role of an ideal house-wife by being Madhavi Bhide in the show has educational qualification in the field of history and fashion designing in real life. This papad selling woman is younger than Aatmaram Bhide in real life.
6- Dilip Joshi started acting in child-plays at the age of 12. His first childplay was “Aie Ranchhod Rangila”. He was supposed to act as a statute for 7-8 minutes in that drama
7- Two important members of the Tapu Sena are cousins in real life. Tapu, played by Bhavya Ganghi and Gogi, played by Samay Shah.
8- Sanskari Daya we see on the show, Disha vakani has been a part of a B-grade entertainer called ‘Kasmin: The Untouched’in 1997. In the movie she did not shy away from skimpy clothes and intimate scenes.
9- Before playing the role of Krishnan Subramaniam Iyer, Tanuj Mahasabde to be the writer of the show. Dilip Joshi however liked the pair of Munmun datta, who plays Babita and Tanuj. They wanted them to be a Bengali-Tamilian couple in the show.
10- bagha character wasn't plan. audience likes him and the character stays permanent. he was playing small roles like Rukmini's husband, taxi driver and school teacher.
11- Gurucharan Singh aka Mr Sodhi is on screen romantic with his Darling Roshan is actually single/unmarried in real life also he owns Personal devlopment classes.
12- Dilip Joshi's character Jethalal has a soft corner for Munmun Datta in TMKOC. But the duo had worked previously in another show called Hum Sab Barati
Source: Google & Youtube